業績一覧

2016年～

• Quan Wu, Yuichi Shichino, Takaya Abe, Taeko Suetsugu, Ayaka Omori, Hiroshi Kiyonari, Shintaro Iwasaki, Fumio Matsuzaki
  Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells

  Nat Commun. 2022 Jan 25;13(1):470. doi: 10.1038/s41467-022-28097-y.

• Mase S, Shitamukai A, Wu Q, Morimoto M, Gridley T, Matsuzaki F.
  Notch1 and Notch2 collaboratively maintain radial glial cells in mouse neurogenesis.

  Neurosci Res. 2020 Dec 11:S0168-0102(20)30492-2. doi: 10.1016/j.neures.2020.11.007.

• Fujita I, Shitamukai A, Kusumoto F, Mase S, Suetsugu T, Omori A, Kato K, Abe T, Shioi G, Konno D, Matsuzaki F.
  Endfoot regeneration restricts radial glial state and prevents translocation into the outer subventricular zone in early mammalian brain development.

  Nat Cell Biol. 2020 Jan;22(1):26-37. doi: 10.1038/s41556-019-0436-9. Epub 2019 Dec 23.

• Konno D, Kishida C, Maehara K, Ohkawa Y, Kiyonari H, Okada S, Matsuzaki F.
  Dmrt factors determine the positional information of cerebral cortical progenitors via differential suppression of homeobox genes.

  Development. 2019 Aug 13;146(15). pii: dev174243. doi: 10.1242/dev.174243.

• Kono K, Yoshiura S, Fujita I, Okada Y, Shitamukai A, Shibata T, Matsuzaki F.
  Reconstruction of Par-dependent polarity in apolar cells reveals a dynamic process of cortical polarization.

  Elife. 2019 Jun 7;8. pii: e45559. doi: 10.7554/eLife.45559.

• Kawaue T, Shitamukai A, Nagasaka A, Tsunekawa Y, Shinoda T, Saito K, Terada R, Bilgic M, Miyata T, Matsuzaki F, Kawaguchi A.
  Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development.

  Nat Commun. 2019 Jun 25;10(1):2780. doi: 10.1038/s41467-019-10730-y.

• Inoue M, Iwai R, Tabata H, Konno D, Komabayashi-Suzuki M, Watanabe C, Iwanari H, Mochizuki Y, Hamakubo T, Matsuzaki F, Nagata KI, Mizutani KI.
  Prdm16 is crucial for progression of the multipolar phase during neural differentiation of the developing neocortex.

  Development.2017 Feb 1;144(3):385-399. doi: 10.1242/dev.136382.(2017)

• Kosodo Y, Suetsugu T, Kobayashi TJ, Matsuzaki F.
  Systematic time-dependent visualization and quantitation of the neurogenic rate in brain organoids.

  Biochem Biophys Res Commun. 2017 Jan 29;483(1):94-100. doi: 10.1016/j.bbrc.2016.12.187. (2017)

• Wölwer CB, Gödde N, Pase LB, Elsum IA, Lim KY, Sacirbegovic F, Walkley CR, Ellis S, Ohno S, Matsuzaki F, Russell SM, Humbert PO.
  The Asymmetric Cell Division Regulators Par3, Scribble and Pins/Gpsm2 Are Not Essential for Erythroid Development or Enucleation.

  PLoS One. 2017 Jan 17;12(1):e0170295. doi:10.1371/journal.pone.0170295. (2017)

• Keiichiro Suzuki, Yuji Tsunekawa, Reyna Hernandez-Benitez, Jun Wu, Jie Zhu, Euiseok J. Kim, Fumiyuki Hatanaka, Mako Yamamoto, Toshikazu Araoka, Zhe Li, Masakazu Kurita, Tomoaki Hishida, Mo Li, Emi Aizawa, Shicheng Guo, Song Chen, April Goebl, Rupa Devi Soligalla, Jing Qu, Tingshuai Jiang, Xin Fu, Maryam Jafari, Concepcion Rodriguez Esteban, Travis Berggren, Jeronimo Lajara, Estrella Nuñez, Pedro Guillen, Josep M. Campistol, Fumio Matsuzaki, Guang-Hui Liu, Pierre Magistretti, Kun Zhang, Edward M. Callaway, Kang Zhang and Juan Carlos Izpisua Belmonte.
  In vivo genome editing via CRISPR-Cas9 mediated homology-independent targeted integration.

  Nature. doi: 10.1038/nature20565 (2016)

• Tsunekawa Y, Terhune RK, Fujita I, Shitamukai A, Suetsugu T, Matsuzaki F.
  Developing a de novo targeted knock-in method based on in utero electroporation into the mammalian brain.

  Development. 143, 3216-3222. (2016)

• Connor SA, Ammendrup-Johnsen I, Chan AW, Kishimoto Y, Murayama C, Kurihara N, Tada A, Ge Y, Lu H, Yan R, LeDue JM, Matsumoto H, Kiyonari H, Kirino Y, Matsuzaki F, Suzuki T, Murphy TH, Wang YT, Yamamoto T, Craig AM.
  Altered Cortical Dynamics and Cognitive Function upon Haploinsufficiency of the Autism-Linked Excitatory Synaptic Suppressor MDGA2.

  Neuron. 91, 1052-1068. (2016).

• Shimada M, Matsuzaki F, Kato A, Kobayashi J, Matsumoto T, Komatsu K.
  Induction of Excess Centrosomes in Neural Progenitor Cells during the Development of Radiation-Induced Microcephaly.

  PLoS One. 11(7):e0158236. doi: 10.1371/journal.pone.0158236. (2016)

• Okamoto M, Miyata T, Konno D, Ueda HR, Kasukawa T, Hashimoto M, Matsuzaki F, and Kawaguchi A.
  Cell cycle–independent transitions in temporal identity of mammalian neural progenitor cells.

  Nat Commun. 7:11349, doi: 10.1038/ncomms11349 (2016)

2011年～2015年

• Konno D, Kasukawa T, Hashimoto K, Itoh T, Suetsugu T, Miura I, Wakana S, Carninci P, Matsuzaki F.
  STAP cells are derived from ES cells.

  Nature. 525, 4-5 (2015)

• Matsuzaki F, Shitamukai A.
  Cell division modes and cleavage planes of neural progenitors during mammalian cortical development.

  Cold Spring Harb Perspect Biol. 2015 Sep 1;7(9):a015719. doi: 10.1101/cshperspect.a015719. (2015)

• Klotz L, Norman S, Vieira JM, Masters M, Rohling M, Dubé KN, Bollini S, Matsuzaki F, Carr CA, Riley PR.
  Cardiac lymphatics are heterogeneous in origin and respond to injury.

  Nature. 522, 62-67. (2015)

• Kasahara K, Kawakami Y, Kiyono T, Yonemura S, Kawamura Y, Era S, Matsuzaki F, Goshima N, Inagaki M.
  Ubiquitin-proteasome system controls ciliogenesis at the initial step of axoneme extension.

  Nat Commun. 5, doi: 10.1038/ncomms6081. (2014)

• Jones C, Qian D, Kim SM, Li S, Ren D, Knapp L, Sprinzak D, Avraham KB, Matsuzaki F, Chi F, Chen P.
  Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear.

  Dev Biol. 395, 62-72.(2014)

• Mora-Bermúdez F, Matsuzaki F, Huttner WB.
  Specific polar subpopulations of astral microtubules control spindle orientation and symmetric neural stem cell division.

  Elife. 3, doi: 10.7554/eLife.02875. (2014)

• Pilz GA, Shitamukai A, Reillo I, Pacary E, Schwausch J, Stahl R, Ninkovic J, Snippert HJ, Clevers H, Godinho L, Guillemot F, Borrell V, Matsuzaki F, Götz M.
  Amplification of progenitors in the mammalian telencephalon includes a new radial glial cell type.

  Nat Commun. 4:2125. doi: 10.1038/ncomms3125 (2013)

• Matsuzaki F, and Shitamukai A.
  Cell division modes and cleavage planes of neural progenitors during mammalian cortical development.

  Cold Spring Harb Perspect Biol. Mammalian Develop. doi 10.1101/cshperspect.a015719 in press.

• Moon W, and Matsuzaki F.
  Aurora A kinase negatively regulates Rho-kinase by phosphorylation in vivo.

  Biochem Biophys Res Commun. doi:pii: S0006-291X(13)00810-3. 10.1016/j.bbrc.2013.05.028. (2013).

• Shimozawa T, Yamagata K, Kondo T, Hayashi S, Shitamukai A, Konno D, Matsuzaki F, Takayama J, Onami S, Nakayama H, Kosugi Y, Watanabe TM, Fujita K, and Mimori-Kiyosue Y.
  Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging.

  Proc Natl Acad Sci U S A. 110, 3399-3404. doi: 10.1073/pnas.1216696110 (2013).

• Konno D, Iwashita M, Satoh Y, Momiyama A, Abe T, Kiyonari H, Matsuzaki F.
  The mammalian DM domain transcription factor Dmrta2 is required for early embryonic development of the cerebral cortex.

  PLoS One. 2012;7(10):e46577

• Shitamukai A, Matsuzaki F.
  Control of asymmetric cell division of mammalian neural progenitors.

  Dev Growth Differ. 2012 Apr;54(3):277-86.

• Yoshiura S, Ohta N, Matsuzaki F.
  Tre1 GPCR signaling orients stem cell divisions in the Drosophila central nervous system.

  Dev Cell. 2012 Jan 17;22(1):79-91. doi: 10.1016/j.devcel.2011.10.027. Epub 2011 Dec 15.

• Kosodo Y, Suetsugu T, Suda M, Mimori-Kiyosue Y, Toida K, Baba SA, Kimura A, Matsuzaki F.
  Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain.

  EMBO J. 2011 May 4;30(9):1690-704. Epub 2011 Mar 25.

• Shitamukai A, Konno D, Matsuzaki F.
  Oblique radial glial divisions in the developing mouse neocortex induce self-renewing progenitors outside the germinal zone that resemble primate outer subventricular zone progenitors.

  J Neurosci. 2011 Mar 9;31(10):3683-95.

2006年～2010年

• Kitajima A, Fuse N, Isshiki T, Matsuzaki F.
  Progenitor properties of symmetrically dividing Drosophila neuroblasts during embryonic and larval development.

  Dev Biol. 2010 Nov 1;347(1):9-23. Epub 2010 Jul 1.

• Ogawa H, Ohta N, Moon W, Matsuzaki F.
  Protein phosphatase 2A negatively regulates aPKC signaling by modulating phosphorylation of Par-6 in Drosophila neuroblast asymmetric divisions.

  J Cell Sci. 2009 Sep 15;122(Pt 18):3242-9. Epub 2009

• Shioi G, Konno D, Shitamukai A, Matsuzaki F.
  Structural basis for self-renewal of neural progenitors in cortical neurogenesis.

  Cereb Cortex. 2009 Jul;19 Suppl 1:i55-61. Epub 2009 Apr 10.

• Kawaguchi A, Ikawa T, Kasukawa T, Ueda HR, Kurimoto K, Saitou M, Matsuzaki F.
  Single-cell gene profiling defines differential progenitor subclasses in mammalian neurogenesis.

  Development. 2008 Sep;135(18):3113-24.

• Konno D, Shioi G, Shitamukai A, Mori A, Kiyonari H, Miyata T, Matsuzaki F.
  Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis.

  Nat Cell Biol.100, 93-101 (2008)

• Matsuzaki F, and Sampath K.
  Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization.

  Nat. Cell Biol. 8, 586-593 (2006).

• Izumi, Y., Ohta, N., Hisata K., Raabe, T. and Matsuzaki, F.
  Drosophila Pins-binding protein Mud regulates spindle-polarity coupling and centrosome organization.

  Nat. Cell Biol. 8, 586-593 (2006).

2001年～2005年

• Matsuzaki, F.
  Drosophila G-protein signalling: intricate roles for Ric-8?

  Nat. Cell Biol. 7, 1047-1049 (2005).

• Kawaguchi, A., Ogawa, M., Saito, K., Matsuzaki, F., Okano, H. and Miyata, T.
  Differential expression of Pax6 and Ngn2 between pair-generated cortical neurons.

  J. Neurosc. Res., 78, 784-795 (2004).

• Izumi, Y., Ohta, N., Itoh-Furuya, A., Fuse, N. and Matsuzaki, F.
  Differential functions of G protein and Baz/aPKC signaling pathways in Drosophila neuroblast asymmetric division.

  J. Cell Biol., 164, 729-738 (2004).

• Fuse, N., Hisata, K., Katzen, L.A. and Matsuzaki, F.
  Heterotrimeric G proteins regulate daughter cell size asymmetry in Drosophila neuroblast divisions.

  Curr. Biol., 13, 947-954 (2003).

1996年～2000年

• Matsuzaki, F.
  Asymmetric division of Drosophila neural stem cells: a basis for neural diversity.

  Curr. Opin. Neurobiol.,10, 38-44 (2000).

• Ohshiro, T., Yagami, T, Zhang, C. and Matsuzaki, F.
  Role of cortical tumor suppressor proteins in asymmetric division of Drosophila neuroblast.

  Nature, 408, 593-596 (2000).

• Torii, M., Matsuzaki, F., Osumi, N., Kaibuchi, K., Nakamura, S., Casarosa, S., Guillemot, F. and Nakafuku, M.
  Transcription factors Mash-1 and Prox-1 delineate early steps in differentiation of neural stem cells in the developing central nervous system.

  Development, 126, 443-456(1999).

• Matsuzaki, F., Ohshiro, T., Ikeshima-Kataoka, H. and Izumi, H.
  Miranda localizes staufen and prospero asymmetrically in mitotic neuroblasts and epithelial cells in early Drosophila embryogenesis.

  Development, 125, 4089-4098 (1998).

• Nakagoshi, H., Hoshi, M., Nabeshima, Y. and Matsuzaki, F.
  A novel homeobox gene mediates the Dpp signal to establish functional specificity within target cells.

  Genes Dev., 12, 2724-2734 (1998).

• Ikeshima-Kataoka, H., Skeath, J. B., Nabeshima, Y., Doe C. Q. and Matsuzaki, F.
  Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions.

  Nature, 390, 625-629 (1997).

• Hirata, J., Nakagoshi, H., Nabeshima, Y. and Matsuzaki, F.
  Asymmetric segregation of the homeodomain protein Prospero during Drosophila development.

  Nature, 377, 627-603 (1995).

1992年～1995年

• Matsuzaki, F., Koizumi, K., Hama, C., Yoshioka, T. and Nabeshima, Y.
  Cloning of the Drosophila prospero Gene and Its Expression in Ganglion Mother Cells.

  Biochem. Biophys. Res. Comm., 182, 1326-1332 (1992).